Yes. You can use a single mesh router. For example, the TP-Link Deco AX3000 WiFi 6 Mesh System Deco X55- is a 1 pack mesh wifi router which you can use for setting up your network.
The mesh router supports wifi 6 and an area of 2500 sqft and replaces your exisiting wireless router and extender.
Single mesh router benefit
The biggest benefit of using a mesh router over a normal router is improved coverage area and better connectivity. It should be noted that a single mesh router is recommended for a smaller area.
A traditional router may not have the necessary range to cover all areas in a home. The signals may also be affected due to physical obstruction.
When the area is large, it is always recommended to purchase a 2 pack or 3 pack mesh system for the best coverage and quality.
Recommended Mesh Wifi routers
This is a dual band router which supports 400Mbps for 2.4GHz + 867Mbps for 5GH. It has advanced featues like reduced buffering and ideal for 4K streaming.
It provides better coverage than traditional wifi routers and has the flexibility to add more routers to create a larger mesh network.
The Deco XE75 has the capacitiy to work as a single mesh WiFi Router. It is also compatible with all the TP-Link Deco Mesh WiFi.
It suppoprts 6 GHz Band which eliminates interference from all legacy devices.